Cloud Computing cost and energy optimization through Federated Cloud SoS

2017 Fall.Includes bibliographical references.The two most significant differentiators amongst contemporary Cloud Computing service providers have increased green energy use and datacenter resource utilization. This work addresses these two issues from a system's architectural optimization viewpoint. The proposed approach herein, allows multiple cloud providers to utilize their individual computing resources in three ways by: (1) cutting the number of datacenters needed, (2) scheduling available datacenter grid energy via aggregators to reduce costs and power outages, and lastly by (3) utilizing, where appropriate, more renewable and carbon-free energy sources. Altogether our proposed approach creates an alternative paradigm for a Federated Cloud SoS approach. The proposed paradigm employs a novel control methodology that is tuned to obtain both financial and environmental advantages. It also supports dynamic expansion and contraction of computing capabilities for handling sudden variations in service demand as well as for maximizing usage of time varying green energy supplies. Herein we analyze the core SoS requirements, concept synthesis, and functional architecture with an eye on avoiding inadvertent cascading conditions. We suggest a physical architecture that diminishes unwanted outcomes while encouraging desirable results. Finally, in our approach, the constituent cloud services retain their independent ownership, objectives, funding, and sustainability means. This work analyzes the core SoS requirements, concept synthesis, and functional architecture. It suggests a physical structure that simulates the primary SoS emergent behavior to diminish unwanted outcomes while encouraging desirable results. The report will analyze optimal computing generation methods, optimal energy utilization for computing generation as well as a procedure for building optimal datacenters using a unique hardware computing system design based on the openCompute community as an illustrative collaboration platform. Finally, the research concludes with security features cloud federation requires to support to protect its constituents, its constituents tenants and itself from security risks

Nationwide Outbreak of Candida auris Infections Driven by COVID-19 Hospitalizations, Israel, 2021–2022

We report an outbreak of Candida auris across multiple healthcare facilities in Israel. For the period of May 2014–May 2022, a total of 209 patients with C. auris infection or colonization were identified. The C. auris incidence rate increased 30-fold in 2021 (p = 0.00015), corresponding in time with surges of COVID-19–related hospitalization. Multilocus sequence typing revealed hospital-level outbreaks with distinct clones. A clade III clone, imported into Israel in 2016, accounted for 48.8% of typed isolates after January 2021 and was more frequently resistant to fluconazole (100% vs. 63%; p = 0.00017) and voriconazole (74% vs. 5.2%; p<0.0001) than were non–clade III isolates. A total of 23% of patients had COVID-19, and 78% received mechanical ventilation. At the hospital level, outbreaks initially involved mechanically ventilated patients in specialized COVID-19 units and then spread sequentially to ventilated non–COVID-19 patients and nonventilated patients